The Binding of Isaac: Rebirth / Items
Isaac Rebirth items guide: active items and useful passives
Recognize common item roles and distinguish original Rebirth effects from later expansion changes.
Edition covered
Original PC Rebirth base game without Afterbirth, Afterbirth+, Repentance or Repentance+. DLC characters, modern room types, expansion bosses and changed Lost unlock rules are outside these guides. Publisher media is from the Rebirth Steam listing.
3 items · one picture per entry · open a picture for full size.
Separate active tools from passive effects

Basic action: Increase damage for the room
Book of Belial
Use it when: A boss or crowded encounter needs faster clearing.

Read passive changes before judging a synergy
More items
- Yum Heart — Restore one Red Heart · A red container has missing health
- The Poop — Create a poop obstacle · You want its breakable obstacle and possible contents
- Spoon Bender — Homing tears · Shots curve toward enemies
- Mutant Spider — Four tears per shot with slower firing · A wider volley and longer gap
- Magic Mushroom — Health and several stat improvements · A broader stat boost rather than a new firing mode
Quick notes
- Separate active tools from passive effects. An active item occupies the usable item slot and normally needs charge to work again.
- Read passive changes before judging a synergy. A passive can alter tear behavior rather than simply raising damage.
- Treat a strong pickup as part of a build. Spoon Bender adds homing, while Mutant Spider creates a wider multi-shot pattern with a slower firing rhythm.
- Use the right edition reference. Rebirth, Afterbirth and Repentance can give the same named item different interactions.
Useful tip
An unfamiliar item can change the timing of your attacks. Test it in the cleared room before opening the next door.
References
| Reference | Website |
|---|---|
| Yum Heart | bindingofisaacrebirth.wiki.gg |
| The Book of Belial | bindingofisaacrebirth.wiki.gg |
| The D6 | bindingofisaacrebirth.wiki.gg |
| The Poop | bindingofisaacrebirth.wiki.gg |
| Spoon Bender | bindingofisaacrebirth.wiki.gg |
| Mutant Spider | bindingofisaacrebirth.wiki.gg |
| Brimstone | bindingofisaacrebirth.wiki.gg |
| Magic Mushroom | bindingofisaacrebirth.wiki.gg |

