The Binding of Isaac adventure archiveThe Binding of IsaacGUIDES
The Binding of Isaac / Characters guide

The Binding of Isaac characters: roles, abilities and story connections

Starting equipment and health make these original-edition characters play differently even when they find the same item.

Edition covered

The 2011 Flash game and its free base-game updates. Wrath of the Lamb and its Eternal Edition changes are excluded unless named for comparison. Rebirth, Afterbirth and Repentance have different unlocks. Pictures are from the original Steam app, including one between-floor dream scene.

5 characters · one picture per entry · open a picture for full size.

Characters

Isaac in The Binding of Isaac
Starting character

Isaac

Begins with three red heart containers and a bomb.

Reference

Cain in The Binding of Isaac
Unlockable survivor

Cain

Starts with Lucky Foot, a key and two red heart containers.

Reference

Judas in The Binding of Isaac
Unlockable survivor

Judas

Starts with Book of Belial, three coins and one red heart container.

Reference

Mom in The Binding of Isaac
Major boss

Mom

The first run-ending obstacle in Depths II.

Reference

Quick notes

  • Key characters and figures. Starting equipment and health make these original-edition characters play differently even when they find the same item.
  • Starting loadouts compared. Red-heart counts are starting containers, before any items found during the run.
  • Choose Magdalene for a forgiving health pool. Her slower movement needs care, but four starting containers and repeatable healing give new players more recovery between fights.
  • Treat Judas as fragile from the first room. His damage advantage does not protect the single starting heart.
References
Guide references
ReferenceWebsite
The Binding of Isaac publisher listingstore.steampowered.com
Original Isaac: Magdalenebindingofisaac.fandom.com
Original Isaac: Cainbindingofisaac.fandom.com
Original Isaac: Judasbindingofisaac.fandom.com
Original Isaac: Roomsbindingofisaac.fandom.com
Original Isaac: Itemsbindingofisaac.fandom.com