BioShock 2 adventure archiveBioShock 2GUIDES
BioShock 2 / Little Sisters

BioShock 2 Little Sisters: adopt, gather, rescue and Big Sister preparation

Understand ADAM collection and the choices that follow each Little Sister.

Edition covered

Original 2010 BioShock 2 single-player story and core systems. Cover art is from the original PC release; gallery pictures show the enhanced BioShock 2 Remastered campaign. Multiplayer and Minerva’s Den have separate content and are excluded.

Adopt to gather before the final choice

BioShock 2 Remastered shows a dark, flooded Rapture interior with a figure beyond the water.
BioShock 2 Remastered shows a dark, flooded Rapture interior with a figure beyond the water.

After dealing with her protector, a Little Sister can be adopted instead of harvested immediately. Carry her to suitable ADAM-bearing bodies, then protect her while she gathers.

Little Sister flow
StepActionPurpose
Protector encounterDefeat the Big Daddy when readyGain access to the Little Sister
AdoptionCarry the Little SisterEnables ADAM gathering
GatheringPlace her at a highlighted suitable bodyEarn ADAM while defending
Vent decisionRescue or harvestResolve her fate and rewards
Big Sister warningPrepare a defensible areaMeet a dangerous follow-up threat

Prepare the room before setting her down

Gathering attracts attackers. Hack usable security, place Trap Rivets or other traps and identify a firing position with sight of the Little Sister before starting.

Defense preparation
ToolUsePlacement idea
Trap RivetsDamage approaching attackersLikely approach lanes
Hacked turretAutomatic allied fireA line covering the gathering area
Security botMobile supportBring it before starting
Electro BoltBriefly disable a threatInterrupt an attacker near the Sister
First Aid and EVEMaintain survival and powersRefill before the fight

Rescue and harvest are different decisions

At the appropriate vent, rescuing or harvesting resolves the Little Sister’s fate. The choice affects the story; gathering first is a separate activity from that final decision.

Use the Big Sister warning to prepare

Big Sister encounters follow progress with Little Sisters. When warned, replenish health, EVE and ammunition and choose a room with movement space rather than entering the fight in a narrow dead end.

Useful tip

Big Sister encounters follow progress with Little Sisters.

References
Guide references
ReferenceWebsite
BioShock 2 publisher listingstore.steampowered.com
Official BioShock 2 PC manualstore.steampowered.com